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Understanding Your Tirzepatide Dosing (20mg/mL vs. 10mg/mL)
Understanding Your Tirzepatide Dosing (20mg/mL vs. 10mg/mL)
Updated over a month ago

Switching to a new concentration of your Tirzepatide medication can feel confusing at first. Your current vial is 20mg per mL, which means it’s twice as concentrated as the 10mg per mL vial you may have used before. Here’s a clear explanation to help you measure your correct dose.


What does "20mg/mL" mean?

This concentration means that each 1 milliliter (mL) of liquid contains 20 milligrams (mg) of Tirzepatide.

  • If you used a 10mg/mL vial before, the same dose will now require half the number of units because this vial is twice as strong.


Doses and Units

Use the table below to see how many units you’ll draw for your prescribed dose:

Dose (mg)

Units to Draw (20mg/mL)

Units to Draw (10mg/mL)

2.5mg

12.5 units

25 units

5mg

25 units

50 units

7.5mg

37.5 units

75 units

10mg

50 units

100 units

12.5mg

62.5 units

125 units

15mg

75 units

150 units


Why the Units Are Different

The difference lies in the concentration of the medication:

  • 20mg/mL vial: You’ll draw fewer units because the medication is more concentrated (more medicine in less liquid).

  • 10mg/mL vial: You needed more liquid (more units) to achieve the same dose.

For example:

  • A 5mg dose required 50 units with the 10mg/mL vial.

  • The same 5mg dose now only requires 25 units with the 20mg/mL vial.


Tips to Avoid Confusion

  1. Always verify your dose in milligrams (mg): Match it to the correct number of units based on the concentration of your vial.

  2. Label your syringes: If you still have 10mg/mL vials on hand, clearly mark them to avoid accidentally drawing the wrong amount.

  3. Ask for support: If you’re ever unsure about your dose or units, reach out to your provider or pharmacist for assistance.


By understanding how the concentration affects the number of units you draw, you’ll feel confident in taking your medication correctly. The 20mg/mL vial simply means you’re using less liquid to get the same dose, but the medication itself remains just as effective!

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